ΠΠ΅ΡΠ΅ΡΡΡΠΎΠΉΠΊΠΈ Π² Π³Π΅Π½ΠΎΠΌΠ΅ Mycoplasma gallisepticum
ΠΠ° ΡΡΠ±Π΅ΠΆΠ΅ XX—Π₯Π₯1 Π²Π΅ΠΊΠΎΠ² ΡΡΠ°Π»ΠΈ Π°ΠΊΡΠΈΠ²Π½ΠΎ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡΡΡ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ ΠΎΡΠ΄Π΅Π»ΡΠ½ΡΠ΅ Π³Π΅Π½Ρ, Π½ΠΎ ΠΈ ΠΏΠΎΠ»Π½ΡΠ΅ Π³Π΅Π½ΠΎΠΌΡ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠΎΠ². Π‘ΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄ΠΎΠ² ΡΠ΅Π»ΡΡ Π³Π΅Π½ΠΎΠΌΠΎΠ² Π΄Π°Π»ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΏΠΎΡΡΠ°Π²ΠΈΡΡ Π²ΠΎΠΏΡΠΎΡΡ ΠΎ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΌ ΡΠΈΡΠ»Π΅ Π³Π΅Π½ΠΎΠ², Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΠΌ Π΄Π»Ρ ΠΆΠΈΠ·Π½Π΅Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΊΠ»Π΅ΡΠΊΠΈ. ΠΠΎΠ΄ΡΡΠ΅Ρ, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠΉ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠ°Π·Π½ΡΡ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠΉ, Π΄Π°Π΅Ρ ΠΎΡΠ΅Π½ΠΊΡ ΡΠΈΡΠ»Π° ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π½Π°Π±ΠΎΡΠ° Π² 250β350 Π³Π΅Π½ΠΎΠ². ΠΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌΡ… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
- Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΡΠ΄Π΅ΡΠΆΠΊΠ°
- ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ°
- ΠΡΡΠ³ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ
- ΠΠΎΠΌΠΎΡΡ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ
Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- 1. Π‘ΠΠΠ‘ΠΠ Π‘ΠΠΠ ΠΠ©ΠΠΠΠ
- 2. ΠΠΠΠΠΠΠΠ
- 3. ΠΠΠΠΠ ΠΠΠ’ΠΠ ΠΠ’Π£Π Π«
- 3. 1. ΠΠ±ΡΠ°Ρ Ρ Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ° ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 2. Π‘ΡΡΡΠΊΡΡΡΠ° ΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΡ Π³Π΅Π½ΠΎΠΌΠ° ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 2. 1. ΠΠΎΠ²ΡΠΎΡΡΡΡΠΈΠ΅ΡΡ ΡΠ»Π΅ΠΌΠ΅Π½ΡΡ Π² Π³Π΅Π½ΠΎΠΌΠ°Ρ
ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 2. 1. 1. Π₯Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ° ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²Π° Π²Π°ΡΠΈΠ°Π±Π΅Π»ΡΠ½ΡΡ Π³Π΅Π½ΠΎΠ² vlhA Π² Π«. gallisepticum
- 3. 2. 1. 2. Π’ΠΈΠΏΡ ΠΏΠΎΠ²ΡΠΎΡΡΡΡΠΈΡ ΡΡ ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 2. 2. Π‘ΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· Π³Π΅Π½ΠΎΠΌΠΎΠ² ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 2. 1. ΠΠΎΠ²ΡΠΎΡΡΡΡΠΈΠ΅ΡΡ ΡΠ»Π΅ΠΌΠ΅Π½ΡΡ Π² Π³Π΅Π½ΠΎΠΌΠ°Ρ
ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 3. Π‘ΠΈΡΡΠ΅ΠΌΡ ΡΠ΅ΠΏΠ°ΡΠ°ΡΠΈΠΈ ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ
- 3. 3. 1. ΠΠ²ΡΡΠ΅ΠΏΠΎΡΠ΅ΡΠ½ΡΠ΅ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡ ΠΠΠ
- 3. 3. 2. ΠΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ ΡΠ΅ΠΏΠ°ΡΠ°ΡΠΈΠΈ Π΄Π²ΡΡΠ΅ΠΏΠΎΡΠ΅ΡΠ½ΡΡ ΡΠ°Π·ΡΡΠ²ΠΎΠ²
- 3. 3. 3. Π Π΅ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΠΎΠ½Π½Π°Ρ ΡΠ΅ΠΏΠ°ΡΠ°ΡΠΈΡ
- 3. 3. 4. SOS-ΠΎΡΠ²Π΅Ρ ΠΈ ΠΏΡΡΠΌΠ°Ρ ΡΠ΅Π°ΠΊΡΠΈΠ²Π°ΡΠΈΡ
- 3. 3. 5. Π Π΅ΠΏΠ°ΡΠ°ΡΠΈΡ Π½Π΅ΡΠΏΠ°ΡΠ΅Π½Π½ΡΡ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄ΠΎΠ²
- 3. 3. 6. ΠΠΊΡΡΠΈΠ·ΠΈΠΎΠ½Π½Π°Ρ ΡΠ΅ΠΏΠ°ΡΠ°ΡΠΈΡ
- 3. 4. ΠΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΡ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ Π³Π΅Π½ΠΎΠΌΠ½ΡΡ
ΠΏΠ΅ΡΠ΅ΡΡΡΠΎΠ΅ΠΊ
- 3. 4. 1. Π’ΠΈΠΏΡ ΡΠ΅ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΠΈ
- 3. 4. 2. ΠΠΎΠ±ΠΈΠ»ΡΠ½ΡΠ΅ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ»Π΅ΠΌΠ΅Π½ΡΡ
ΠΠ΅ΡΠ΅ΡΡΡΠΎΠΉΠΊΠΈ Π² Π³Π΅Π½ΠΎΠΌΠ΅ Mycoplasma gallisepticum (ΡΠ΅ΡΠ΅ΡΠ°Ρ, ΠΊΡΡΡΠΎΠ²Π°Ρ, Π΄ΠΈΠΏΠ»ΠΎΠΌ, ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½Π°Ρ)
ΠΠ° ΡΡΠ±Π΅ΠΆΠ΅ XX—Π₯Π₯1 Π²Π΅ΠΊΠΎΠ² ΡΡΠ°Π»ΠΈ Π°ΠΊΡΠΈΠ²Π½ΠΎ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡΡΡ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ ΠΎΡΠ΄Π΅Π»ΡΠ½ΡΠ΅ Π³Π΅Π½Ρ, Π½ΠΎ ΠΈ ΠΏΠΎΠ»Π½ΡΠ΅ Π³Π΅Π½ΠΎΠΌΡ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠΎΠ². Π‘ΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄ΠΎΠ² ΡΠ΅Π»ΡΡ Π³Π΅Π½ΠΎΠΌΠΎΠ² Π΄Π°Π»ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΏΠΎΡΡΠ°Π²ΠΈΡΡ Π²ΠΎΠΏΡΠΎΡΡ ΠΎ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΌ ΡΠΈΡΠ»Π΅ Π³Π΅Π½ΠΎΠ², Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΠΌ Π΄Π»Ρ ΠΆΠΈΠ·Π½Π΅Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΊΠ»Π΅ΡΠΊΠΈ. ΠΠΎΠ΄ΡΡΠ΅Ρ, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠΉ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠ°Π·Π½ΡΡ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠΉ, Π΄Π°Π΅Ρ ΠΎΡΠ΅Π½ΠΊΡ ΡΠΈΡΠ»Π° ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π½Π°Π±ΠΎΡΠ° Π² 250−350 Π³Π΅Π½ΠΎΠ². ΠΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌΡ ΠΏΡΠΈΠ²Π»Π΅ΠΊΠ°ΡΠ΅Π»ΡΠ½ΡΠΉ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ Π΄Π»Ρ ΡΠΎΠ±ΠΎΠΉ ΠΊΠ»Π°ΡΡ ΠΎΠ±ΡΠ΅ΠΊΡΠΎΠ², ΠΏΠΎΡΠΊΠΎΠ»ΡΠΊΡ ΠΏΡΠΎΡΡΠΎ ΡΡΠ΅Π·Π²ΡΡΠ°ΠΉΠ½ΠΎ ΡΡΡΠ΅ΡΡΠ²ΡΠ΅Ρ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ, Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΏΠΎΠ»Π½ΠΎΠΉ Ρ Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΠ°ΠΌΠΎΡΠ΅ΠΏΠ»ΠΈΡΠΈΡΡΡΡΠ΅ΠΉΡΡ ΠΊΠ»Π΅ΡΠΊΠΈ. Π§ΠΈΡΠ»ΠΎ Π³Π΅Π½ΠΎΠ² Π² Π³Π΅Π½ΠΎΠΌΠ΅ ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ (ΠΏΡΠΈΠΌΠ΅ΡΠ½ΠΎ 500) Π±Π»ΠΈΠ·ΠΊΠΎ ΠΊ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΌΡ Π½Π°Π±ΠΎΡΡ ΡΠ°ΠΌΠΎΠ²ΠΎΡΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ΅ΠΉΡΡ ΠΊΠ»Π΅ΡΠΊΠΈ. ΠΠ½Π°Π»ΠΈΠ· ΠΏΠΎΠ»Π½ΡΡ Π³Π΅Π½ΠΎΠΌΠΎΠ² ΠΎΡΠΊΡΡΠ²Π°Π΅Ρ ΠΏΠ΅ΡΠ΅Π΄ Π½Π°ΠΌΠΈ ΡΠΎΠ½ΠΊΠΈΠ΅ Π΄Π΅ΡΠ°Π»ΠΈ ΡΡΡΡΠΎΠΉΡΡΠ²Π° Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ. ΠΠ°ΠΏΡΠΈΠΌΠ΅Ρ, Π²ΡΡΡΠ½ΠΈΠ»ΠΎΡΡ, ΡΡΠΎ, Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ Π³Π΅Π½ΠΎΠ² ΠΏΡΠΎΠΊΠ°ΡΠΈΠΎΡ ΡΡΠ°Π½ΡΠΊΡΠΈΠ±ΠΈΡΡΠ΅ΡΡΡ ΠΏΠΎ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΡ ΡΠ΅ΠΏΠ»ΠΈΠΊΠ°ΡΠΈΠ²Π½ΠΎΠΉ Π²ΠΈΠ»ΠΊΠΈ. ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, ΠΏΠΎΠ»ΡΡΠΈΠ»Π° Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅Π΅ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½ΠΈΠ΅ Π³ΠΈΠΏΠΎΡΠ΅Π·Π° ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΌΠ΅ΠΆΠ²ΠΈΠ΄ΠΎΠ²ΠΎΠ³ΠΎ (Π³ΠΎΡΠΈΠ·ΠΎΠ½ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ) ΠΏΠ΅ΡΠ΅Π½ΠΎΡΠ° Π³Π΅Π½ΠΎΠ². ΠΠ±Π½Π°ΡΡΠΆΠΈΠ²Π°ΡΡΡΡ Π½ΠΎΠ²ΡΠ΅ ΡΠ°ΠΊΡΡ, ΡΠ²ΡΠ·Π°Π½Π½ΡΠ΅ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ Ρ ΠΏΠΎΠΈΡΠΊΠΎΠΌ ΠΈ Π°Π½Π½ΠΎΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠ°Π½Π΅Π΅ Π½Π΅ΠΈΠ·Π²Π΅ΡΡΠ½ΡΠ³Ρ Π³Π΅Π½ΠΎΠ², Π½ΠΎ ΠΈ Ρ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ ΠΏΠ΅ΡΠ΅ΡΡΡΠΎΠΉΠΊΠ°ΠΌΠΈ Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ. Π ΡΠ°ΡΡΠ½ΠΎΡΡΠΈ, ΠΏΡΠΈ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠΈ ΠΏΠΎΡΡΠ΄ΠΊΠ° ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π³Π΅Π½ΠΎΠ² Π² ΡΠ°Π·Π½ΡΡ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ°Ρ , ΠΏΡΠΈΡΡΠ°Π»ΡΠ½ΠΎΠ΅ Π²ΡΡΡΠ½ΠΈΠ»ΠΎΡΡ, ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΠΎ ΠΏΠΎΡΡΠ΄ΠΎΠΊ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΡΡΠΎΡ Π½Π΅ΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π΅Π½. ΠΠΎΠ»Π΅Π΅ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΎ, ΡΡΠΎ Π½Π° ΠΊΠΎΡΠΎΡΠΊΠΈΡ ΡΠ°ΡΡΡΠΎΡΠ½ΠΈΡΡ , ΠΊΠ°ΠΊ ΠΏΡΠ°Π²ΠΈΠ»ΠΎ, ΠΏΠΎΡΡΠ΄ΠΎΠΊ Π³Π΅Π½ΠΎΠ² ΡΠΎΡ ΡΠ°Π½ΡΠ΅ΡΡΡ, ΡΠΎ Π΅ΡΡΡ Π±ΠΎΠ»Π΅Π΅ ΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½ΡΠΌ ΡΠ²Π»ΡΠ΅ΡΡΡ Π±Π»ΠΈΠΆΠ½ΠΈΠΉ ΠΏΠΎΡΡΠ΄ΠΎΠΊ Π³Π΅Π½ΠΎΠ², ΠΏΡΠΈΡΠ΅ΠΌ Π΄Π»ΠΈΠ½Π° ΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½ΡΡ ΡΡΠ°ΡΡΠΊΠΎΠ² Π² Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²Π΅ ΡΠ»ΡΡΠ°Π΅Π² ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ΅ΡΡΡ ΡΠ°Π·ΠΌΠ΅ΡΠΎΠΌ ΠΎΠΏΠ΅ΡΠΎΠ½Π°. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, Π³Π΅Π½ΠΎΠΌ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ ΡΠΎΠ±ΠΎΠΉ Π΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΡΡ ΡΡΡΡΠΊΡΡΡΡ, Π² ΠΊΠΎΡΠΎΡΠΎΠΉ ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡ ΠΎΠ±ΠΌΠ΅Π½ ΡΠ°ΡΡΡΠΌΠΈ, ΠΈ Π΅Π΄ΠΈΠ½ΠΈΡΠ΅ΠΉ ΠΎΠ±ΠΌΠ΅Π½Π° ΡΠ°ΡΠ΅ Π²ΡΠ΅Π³ΠΎ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠΏΠ΅ΡΠΎΠ½. ΠΡΠΈ Π°Π½Π°Π»ΠΈΠ·Π΅ Π³ΡΠ°Π½ΠΈΡ ΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½ΡΡ ΡΡΠ°ΡΡΠΊΠΎΠ² Π±ΡΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ ΡΡΠΈΡ ΠΏΠ΅ΡΠ΅ΡΡΡΠΎΠ΅ΠΊ ΡΠ²ΡΠ·Π°Π½ΠΎ Ρ ΠΏΠ΅ΡΠ΅ΠΌΠ΅ΡΠ΅Π½ΠΈΡΠΌΠΈ ΠΌΠΎΠ±ΠΈΠ»ΡΠ½ΡΡ ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² ΠΈΠ»ΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠΌ Π³ΠΎΠΌΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΠΎΠΉ ΡΠ΅ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΠΈ. ΠΠ΅ΠΊΠΎΡΠΎΡΡΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΡΡΠΎΠ΅Π½ΠΈΡ Π³Π΅Π½ΠΎΠΌΠ° ΠΎΡΡΠ°ΡΡΡΡ ΠΏΠΎΠΊΠ° Π½Π΅Π΄ΠΎΡΡΡΠΏΠ½Ρ Π΄Π»Ρ ΠΏΠΎΠ½ΠΈΠΌΠ°Π½ΠΈΡ, ΠΏΠΎΡΠΊΠΎΠ»ΡΠΊΡ Π½Π΅ΠΏΠΎΠ½ΡΡΠ½Ρ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ ΠΈΡ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ. Π ΡΠ²ΡΠ·ΠΈ Ρ ΡΡΠΈΠΌ Π²ΠΎΠ·Π½ΠΈΠΊΠ°ΡΡ Π·Π°Π΄Π°ΡΠΈ, ΠΈΠΌΠ΅ΡΡΠΈΠ΅ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ Π½Π΅ ΡΡΠΎΠ»ΡΠΊΠΎ ΠΊ ΡΡΡΡΠΊΡΡΡΠ½ΠΎΠΌΡ Π°Π½Π°Π»ΠΈΠ·Ρ Π³Π΅Π½ΠΎΠΌΠ°, ΡΠΊΠΎΠ»ΡΠΊΠΎ ΠΊ ΠΏΠΎΠ½ΠΈΠΌΠ°Π½ΠΈΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠΎΠ² ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ², Π»Π΅ΠΆΠ°ΡΠΈΡ Π² ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ, ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΠΈ ΠΈΠ·ΠΌΠ΅Π½ΡΠΈΠ²ΠΎΡΡΠΈ ΡΡΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ. ΠΠ° ΠΏΡΠΎΡΡΠΆΠ΅Π½ΠΈΠΈ ΠΌΠ½ΠΎΠ³ΠΈΡ Π»Π΅Ρ Π² Π½Π°ΡΠ΅ΠΉ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠΈΠΈ ΠΈΠ·ΡΡΠ°Π»ΠΈ Π±Π°ΠΊΡΠ΅ΡΠΈΡ Mycoplasma gallisepticum. ΠΠ½ΡΠ΅ΡΠ΅Ρ ΠΊ ΠΏΡΠ΅Π΄ΡΡΠ°Π²ΠΈΡΠ΅Π»Ρ ΡΠΎΠ΄Π° Mycoplasma ΡΠ²ΡΠ·Π°Π½ Ρ Π½Π΅Π±ΠΎΠ»ΡΡΠΈΠΌ ΠΎΠ±ΡΠΈΠΌ ΡΠΈΡΠ»ΠΎΠΌ Π³Π΅Π½ΠΎΠ², ΡΡΠΎ Π΄Π΅Π»Π°Π΅Ρ ΠΏΡΠΈΠ²Π»Π΅ΠΊΠ°ΡΠ΅Π»ΡΠ½ΡΠΌ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΌΠΈΠΊΠΎΠΏΠ»Π°Π·ΠΌ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΌΠΎΠ΄Π΅Π»ΠΈ Π΄Π»Ρ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·ΠΈ Π³Π΅Π½ΠΎΠ² Π½Π° ΡΡΠΎΠ²Π½Π΅ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠΈ Π² ΡΠ΅Π»ΠΎΠΉ ΠΊΠ»Π΅ΡΠΊΠ΅. ΠΡΠΈ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠΈ Mycoplasma gallisepticum Π±ΡΠ» ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ ΡΡΠ΄ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ Π² Π³Π΅Π½ΠΎΠΌΠ½ΠΎΠΉ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ. ΠΡΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π²Π°ΡΠΈΠ°Π½ΡΡ ΡΡΠ°ΠΌΠΌΠ° Π5969 ΠΈΠ· ΡΠ°Π·Π½ΡΡ ΠΊΠΎΠ»Π»Π΅ΠΊΡΠΈΠΉ ΠΌΠΎΠ³ΡΡ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΠΎΡΠ»ΠΈΡΠ°ΡΡΡΡ ΠΏΠΎ ΡΠ°Π·ΠΌΠ΅ΡΡ Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ. ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, Π² Π³Π΅Π½ΠΎΠΌΠ΅ ΡΡΠ°ΠΌΠΌΠ° Π5969 Π±ΡΠ»Π° ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Π° ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡ, Π° ΠΈΠΌΠ΅Π½Π½ΠΎ: ΡΠΈΡΠ»ΠΎ Π³Π΅Π½ΠΎΠ² 16S ΡΠ ΠΠ ΡΠ½ΠΈΠΊΠ°Π»ΡΠ½Π°Ρ (ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΠΎΠ΅ ΠΏΠΎ Π³ΠΈΠ±ΡΠΈΠ΄ΠΈΠ·Π°ΡΠΈΠΈ) ΠΎΠΊΠ°Π·Π°Π»ΠΎΡΡ Π½Π΅ ΡΠ°Π²Π½ΡΠΌ ΡΠΈΡΠ»Ρ Π³Π΅Π½ΠΎΠ² 23S ΠΈ 5S ΡΠ ΠΠ. ΠΠΎ Π²ΡΠ΅Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Π½ΡΡ Π΄ΠΎ Π½Π°ΡΡΠΎΡΡΠ΅Π³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ Π±Π°ΠΊΡΠ΅ΡΠΈΡΡ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ Π³Π΅Π½ΠΎΠ² 16S, 23S ΠΈ 5S ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²ΠΎ. ΠΠ°Π»ΡΠ½Π΅ΠΉΡΠΈΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΡΠΎ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½Π°Ρ ΠΊΠΎΠΏΠΈΡ 16S ΡΠ ΠΠ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ ΡΠΎΠ±ΠΎΠΉ Π½Π΅ ΠΏΠΎΠ»Π½ΠΎΡΠ΅Π½Π½ΡΠΉ Π³Π΅Π½, Π° ΡΠΊΠΎΡΠΎΡΠ΅Π½Π½ΡΡ ΠΊΠΎΠ½ΠΈΡ. ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, Π΄Π²Π° Π½Π°Π±ΠΎΡΠ° Π³Π΅Π½ΠΎΠ² ΡΠ ΠΠ ΠΎΡΠ»ΠΈΡΠ°ΡΡΡΡ ΠΏΠΎ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ: Π³Π΅Π½Ρ ΠΏΠ΅ΡΠ²ΠΎΠ³ΠΎ Π½Π°Π±ΠΎΡΠ° ΡΠΈΠ±ΠΎΡΠΎΠΌΠ½ΡΡ Π 1Π ΡΠΎΠ±ΡΠ°Π½Ρ Π² «ΠΊΠ»Π°ΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ» Π΄Π»Ρ ΠΏΡΠΎΠΊΠ°ΡΠΈΠΎΡ ΠΎΠΏΠ΅ΡΠΎΠ½ Ρ ΠΏΠΎΡΡΠ΄ΠΊΠΎΠΌ Π³Π΅Π½ΠΎΠ² 16S 23S 5S ΡΠ ΠΠ, Π²ΠΎ Π²ΡΠΎΡΠΎΠΌ Π½Π°Π±ΠΎΡΠ΅ Π³Π΅Π½ 16S ΡΠ ΠΠ ΠΎΡΠ΄Π΅Π»Π΅Π½ ΠΎΡ ΡΠΎΡΠ΅Π΄ΡΡΠ²ΡΡΡΠΈΡ Π³Π΅Π½ΠΎΠ² 23S 5S ΡΠ 1Π Π½Π° Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ΅ ΡΠ°ΡΡΡΠΎΡΠ½ΠΈΠ΅. ΠΡΠ΅ ΡΡΠΎ Π³ΠΎΠ²ΠΎΡΠΈΡ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΡΠ²ΠΎΠ»ΡΡΠΈΠΈ Ρ Π gallisepticum ΠΏΡΠΎΠΈΠ·ΠΎΡΠ»ΠΈ ΠΊΡΡΠΏΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² ΡΡΡΡΠΊΡΡΡΠ΅ Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ. Π¦Π΅Π»ΡΡ Π½Π°ΡΡΠΎΡΡΠ΅ΠΉ ΡΠ°Π±ΠΎΡΡ Π±ΡΠ»ΠΎ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ², ΠΏΡΠΈΠ²ΠΎΠ΄ΡΡΠΈΡ ΠΊ ΠΊΡΡΠΏΠ½ΡΠΌ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌ Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ. ΠΠ»Ρ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΡΡΠΎΠΉ ΡΠ΅Π»ΠΈ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π»ΠΈΡΡ ΠΏΠ΅ΡΠ΅ΡΡΡΠΎΠΉΠΊΠΈ Π³Π΅Π½ΠΎΠΌΠ° Π gallisepticum ΡΡΠ°ΠΌΠΌ Π5969. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΠΈΠ·ΡΡΠ°Π»ΠΈ ΡΡΡΡΠΊΡΡΡΡ ΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ² ΠΠΠ, ΡΠΎΠ΄Π΅ΡΠΆΠ°ΡΠΈΡ ΡΠΈΠ±ΠΎΡΠΎΠΌΠ½ΡΠ΅ Π ΠΠ, ΠΈ ΠΎΠΊΡΡΠΆΠ°ΡΡΠΈΠ΅ ΠΈΡ ΡΡΠ°ΡΡΠΊΠΈ, Π²ΠΎΠ²Π»Π΅ΡΠ΅Π½Π½ΡΠ΅, Π½ΠΎ-Π²ΠΈΠ΄ΠΈΠΌΠΎΠΌΡ, Π² ΠΏΡΠΎΡΠ΅ΡΡΡ, ΡΠ²ΡΠ·Π°Π½Π½ΡΠ΅ Ρ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ. Π ΡΠ²ΡΠ·ΠΈ Ρ ΡΡΠΈΠΌ Π±ΡΠ»ΠΈ ΠΏΠΎΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ»Π΅Π΄ΡΡΡΠΈΠ΅ Π·Π°Π΄Π°ΡΠΈ: 1 ΠΊΠ°ΡΡΠΈΡΠΎΠ²Π°ΡΡ ΡΡΠ°ΡΡΠΊΠΈ ΠΠΠ Π. gallisepticum ΡΡΠ°ΠΌΠΌ Π5969, ΡΠΎΠ΄Π΅ΡΠΆΠ°ΡΠΈΠ΅ ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½Π½ΡΠΉ ΠΎΠΏΠ΅ΡΠΎΠ½ ΡΠΈΠ±ΠΎΡΠΎΠΌΠ½ΡΡ Π ΠΠ ΠΈ ΡΠΊΠΎΡΠΎΡΠ΅Π½Π½ΡΠΉ Π³Π΅Π½ 16S ΡΠ Π¬Π- 2 ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄ΠΎΠ² ΡΡΠΈΡ ΡΡΠ°ΡΡΠΊΠΎΠ², Π° ΡΠ°ΠΊΠΆΠ΅ ΠΎΠΊΡΡΠΆΠ°ΡΡΠΈΡ ΠΈΡ ΠΎΠ±Π»Π°ΡΡΠ΅ΠΉ Ρ ΡΠΎΠΌΠΎΡΠΎΠΌΡ- 3 —ΠΈΠ·ΡΡΠΈΡΡ ΡΠΎΡΡΠ°Π² ΠΈ ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ Π³Π΅Π½ΠΎΠ², Π° ΡΠ°ΠΊΠΆΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΠΊΠ»Π°ΡΡΠ΅ΡΠΎΠ² Π³Π΅Π½ΠΎΠ² Π² ΠΊΠ°ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ ΡΡΠ°ΡΡΠΊΠ°Ρ - 4 Π²ΡΡΡΠ½ΠΈΡΡ ΡΡΡΡΠΎΠΉΡΡΠ²ΠΎ Π΄Π»ΠΈΠ½Π½ΠΎΠ³ΠΎ ΠΏΡΡΠΌΠΎΠ³ΠΎ ΠΏΠΎΠ²ΡΠΎΡΠ° Π² Π. gallisepticum ΡΡΠ°ΠΌΠΌ Π5969.
7. ΠΠ«ΠΠΠΠ«.
1. Π Π³Π΅Π½ΠΎΠΌΠ΅ Π. § Π°Π¨8Π΅ΡΠΡΠΈΡ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Π° ΠΏΠ΅ΡΠ΅ΡΡΡΠΎΠΉΠΊΠ°, ΠΊΠΎΡΠΎΡΠ°Ρ ΠΏΡΠΈΠ²Π΅Π»Π° ΠΊ ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½ΠΈΡ Π΄Π²ΡΡ Π²ΡΡΠΎΠΊΠΎΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½ΡΡ Π»ΠΎΠΊΡΡΠΎΠ²: ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΈΠ· Π΄Π²ΡΡ ΠΎΠΏΠ΅ΡΠΎΠ½ΠΎΠ² ΡΠΈΠ±ΠΎΡΠΎΠΌΠ½ΡΡ Π ΠΠ ΠΈ ΠΊΠ»Π°ΡΡΠ΅ΡΠ° Π³Π΅Π½ΠΎΠ² ΡΠΈΠ±ΠΎΡΠΎΠΌΠ½ΡΡ Π±Π΅Π»ΠΊΠΎΠ² Π10. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½ΠΈΡ ΠΎΠΏΠ΅ΡΠΎΠ½Π° ΡΠΈΠ±ΠΎΡΠΎΠΌΠ½ΡΡ Π ΠΠ Π³Π΅Π½ 16Π ΡΠ ΠΠ ΠΎΡΠ΄Π΅Π»ΠΈΠ»ΡΡ ΠΎΡ Π³Π΅Π½ΠΎΠ² 23 858 ΡΠ ΠΠ. ΠΠ΅Π½Ρ Ρ/Π, Π³Ρ/36, Π³ΡΡ 13, Π³ΡΠΎΠ, Π³Ρ11, ΠΎΡΠ΄Π΅Π»ΠΈΠ²ΡΠΈΠ΅ΡΡ ΠΎΡ ΠΊΠ»Π°ΡΡΠ΅ΡΠ° 810, ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π»ΠΈ Π½ΠΎΠ²ΡΠΉ ΠΊΠ»Π°ΡΡΠ΅Ρ Ρ Π³Π΅Π½Π°ΠΌΠΈ Ρ, Ρ16, Π³Ρ19. ΠΠ΅Π½Ρ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠ»Π°ΡΡΠ΅ΡΠ° ΡΠΎΡΡΠ°Π²Π»ΡΡΡ Π΅Π΄ΠΈΠ½ΡΠΉ ΠΎΠΏΠ΅ΡΠΎΠ½.
2. Π Π³Π΅Π½ΠΎΠΌΠ΅ ΡΡΠ°ΠΌΠΌΠ° Π5969 Π. ?Π°1Π¨Π΅ΡΠΡΠΈΡ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ Π΄Π»ΠΈΠ½Π½ΡΠΉ ΠΏΡΡΠΌΠΎΠΉ ΠΏΠΎΠ²ΡΠΎΡ, ΡΠΎΡΡΠΎΡΡΠΈΠΉ ΠΈΠ· Π΄Π²ΡΡ ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²ΡΡ ΡΡΠ°ΡΡΠΊΠΎΠ² ΡΠ°Π·ΠΌΠ΅ΡΠΎΠΌ 15 778 ΠΏΠ°Ρ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄ΠΎΠ² (ΠΏΠ»Π΅ΡΠΈ ΠΏΠΎΠ²ΡΠΎΡΠ°), ΡΠ°Π·Π΄Π΅Π»Π΅Π½Π½ΡΡ 30-Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄Π½ΡΠΌ ΡΠΏΠ΅ΠΉΡΠ΅ΡΠΎΠΌ. Π‘ΠΏΠ΅ΠΉΡΠ΅ΡΠ½ΡΠΉ ΡΡΠ°ΡΡΠΎΠΊ ΠΈΠ΄Π΅Π½ΡΠΈΡΠ΅Π½ ΡΡΠ°ΡΡΠΊΡ Π³Π΅Π½Π° Π³Ρ1Π ΠΈΠ· ΠΊΠ»Π°ΡΡΠ΅ΡΠ° 810, ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΠΎΠ³ΠΎ Π² Π΄ΡΡΠ³ΠΎΠΌ Π»ΠΎΠΊΡΡΠ΅ Π³Π΅Π½ΠΎΠΌΠ°. ΠΠ°ΠΆΠ΄ΠΎΠ΅ ΠΏΠ»Π΅ΡΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠΈΡ 15 ΠΏΠΎΠ»Π½ΠΎΡΠ΅Π½Π½ΡΡ ΡΠ°ΠΌΠΎΠΊ ΡΡΠΈΡΡΠ²Π°Π½ΠΈΡ. ΠΠ° ΠΊΠΎΠ½ΡΠ΅ ΠΊΠ°ΠΆΠ΄ΠΎΠ³ΠΎ ΠΏΠ»Π΅ΡΠ° ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ Π³Π΅Π½ 168 ΡΠ ΠΠ, ΠΏΡΠΈΡΠ΅ΠΌ ΠΎΠ΄Π½ΠΎ ΠΈΠ· Π½ΠΈΡ ΡΠΎΠ΄Π΅ΡΠΆΠΈΡ ΠΏΠΎΠ»Π½ΡΡ ΠΊΠΎΠ΄ΠΈΡΡΡΡΡΡ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ 168 ΡΠ ΠΠ, Π° Π΄ΡΡΠ³ΠΎΠ΅ Π·Π°ΠΊΠ°Π½ΡΠΈΠ²Π°Π΅ΡΡΡ ΡΠΊΠΎΡΠΎΡΠ΅Π½Π½ΡΠΌ Π³Π΅Π½ΠΎΠΌ 168 ΡΠ ΠΠ.
3. ΠΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Π° ΠΌΠΎΠ΄Π΅Π»Ρ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠ°Ρ ΠΎΠ±ΡΡΡΠ½ΠΈΡΡ ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½ΠΈΠ΅ ΠΎΠΏΠ΅ΡΠΎΠ½Π° ΡΠ ΠΠ ΠΈ ΠΊΠ»Π°ΡΡΠ΅ΡΠ° 810, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΌΠΎΠ΄Π΅Π»Ρ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ Π΄Π»ΠΈΠ½Π½ΠΎΠ³ΠΎ ΠΏΡΡΠΌΠΎΠ³ΠΎ ΠΏΠΎΠ²ΡΠΎΡΠ°.
4. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π° ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΡ ΠΊΠ»Π°ΡΡΠ΅ΡΠ° Π³Π΅Π½ΠΎΠ² /ΠΡΠ (ΡΠΈΠΌΠΈΠ΄ΠΈΠ»Π°Ρ-ΡΠΈΠ½ΡΠ΅ΡΠ°Π·Ρ) Π² Π. gallisepticum ΡΡΠ°ΠΌΠΌ Π5969. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΠΎΠ΄ΠΈΠ½ ΠΈΠ· Π³Π΅Π½ΠΎΠ² ΡΡΠΎΠ³ΠΎ ΠΊΠ»Π°ΡΡΠ΅ΡΠ° ΠΊΠΎΠ΄ΠΈΡΡΠ΅Ρ ΡΠΎΡΡΠ°Π²Π½ΠΎΠΉ ΠΏΠΎΠ»ΠΈΠΏΠ΅ΠΏΡΠΈΠ΄ — Π΄ΠΈΠ³ΠΈΠ΄ΡΠΎΡΠΎΠ»Π°Ρ-ΡΠ΅Π΄ΡΠΊΡΠ°Π·Ρ-Π΄Π΅Π·ΠΎΠΊΡΠΈΡΠΈΡΠΈΠ΄ΠΈΠ»Π°Ρ-Π΄Π΅Π·Π°ΠΌΠΈΠ½Π°Π·Ρ.
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