Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π½Π΅ΠΉΡΠΎΠ½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΊΡΡΡ
ΠΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ°Π±ΠΎΡΡ Π±ΡΠ»ΠΈ Π΄ΠΎΠ»ΠΎΠΆΠ΅Π½Ρ Π½Π° ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ ΡΠΎΡΡΠΌΠ°Ρ ΠΠ Π (ΠΡΠ»Π°Π½ΡΠ° 2006, Π‘Π°Π½ ΠΠΈΠ΅Π³ΠΎ 2007, Π§ΠΈΠΊΠ°Π³ΠΎ 2009) — XX Π‘ΡΠ΅Π·Π΄Π΅ ΡΠΎΡΡΠΈΠΉΡΠΊΠΈΡ ΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΎΠ² (ΠΠΎΡΠΊΠ²Π°, 2007) — Π½Π° ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΡΡ ΠΌΠΎΠ»ΠΎΠ΄ΡΡ ΡΡΠ΅Π½ΡΡ ΠΠΠΠ ΠΈ ΠΠ€ Π ΠΠ (ΠΠΎΡΠΊΠ²Π°, 2006, 2008). ΠΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΡ Π°ΠΏΡΠΎΠ±ΠΈΡΠΎΠ²Π°Π½Π° 13 ΠΎΠΊΡΡΠ±ΡΡ 2009 Π³ΠΎΠ΄Π° Π½Π° ΡΠΎΠ²ΠΌΠ΅ΡΡΠ½ΠΎΠΌ Π·Π°ΡΠ΅Π΄Π°Π½ΠΈΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠΈΠΈ ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠΉ Π½Π΅ΠΉΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ ΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠΈΠΈ Π½Π΅ΠΉΡΠΎΠΎΠ½ΡΠΎΠ³Π΅Π½Π΅Π·Π° ΠΠ½ΡΡΠΈΡΡΡΠ° Π²ΡΡΡΠ΅ΠΉ… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
- Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΡΠ΄Π΅ΡΠΆΠΊΠ°
- ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ°
- ΠΡΡΠ³ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ
- ΠΠΎΠΌΠΎΡΡ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ
Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΠΠΠΠ I. ΠΠΠΠΠ ΠΠΠ’ΠΠ ΠΠ’Π£Π Π«
- 1. 1. ΠΠΠ’ΠΠ ΠΠΠΠΠ¬ΠΠΠ― ΠΠΠ Π
- 1. 1. 1. Π‘ΡΡΠΎΠ΅Π½ΠΈΠ΅, ΡΠ²ΡΠ·ΠΈ, ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅
- 1. 1. 2. Π ΠΈΡΠΌΠΈΡΠ΅ΡΠΊΠ°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ
- 1. 2. Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅ΠΉΡΡ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ
- 1. 2. 1. ΠΠΈΠΏΠΏΠΎΠΊΠ°ΠΌΠΏ ΠΈ Π½ΠΎΠ²Π°Ρ ΠΊΠΎΡΠ°
- 1. 2. 2. Π‘Π΅ΡΡΠ°ΡΠΊΠ°
- 1. 2. 3. Π ΠΎΠ»Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΡΠ΅ΡΡΠ°ΡΠΊΠΈ Π² ΡΠ°Π·Π²ΠΈΡΠΈΠΈ Π·ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ
- 1. 2. 4. Π‘ΠΏΠΈΠ½Π½ΠΎΠΉ ΠΌΠΎΠ·Π³
- 1. 2. 5. Π‘Π²ΡΠ·Ρ ΠΌΠ΅ΠΆΠ΄Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ ΡΠΏΠΈΠ½Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° ΠΈ ΡΠΎΡΡΠΎΠΌ Π°ΠΊΡΠΎΠ½ΠΎΠ² ΠΌΠΎΡΠΎΠ½Π΅ΠΉΡΠΎΠ½ΠΎΠ²
- 1. 2. 6. ΠΠ΅Ρ Π°Π½ΠΈΠ·ΠΌ Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅ΠΉΡΡ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠ΅
- 1. 1. ΠΠΠ’ΠΠ ΠΠΠΠΠ¬ΠΠΠ― ΠΠΠ Π
- 2. 1. ΠΡΠΈΠ³ΠΎΡΠΎΠ²Π»Π΅Π½ΠΈΠ΅ ΡΡΠ΅Π·ΠΎΠ²
- 2. 2. Π Π°ΡΡΠ²ΠΎΡΡ ΠΈ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ»ΠΎΠ³ΠΈΡ
- 2. 3. ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Π°Ρ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠ°
- 2. 4. Π Π΅Π³ΠΈΡΡΡΠ°ΡΠΈΡ
- 2. 5. ΠΠ±ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²
- 3. 1. Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ
ΠΊΡΡΡ
- 3. 1. 1. ΠΠ²Π° ΡΠΈΠΏΠ° ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ
- 3. 1. 2. ΠΠ΅Π½Π΅ΡΠ°ΡΠΈΡ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡ Ρ ΡΡΠ°ΡΡΠΈΠ΅ΠΌ ΠΠΠΠΠ΅ΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΠ½Π°ΠΏΡΠΎΠ²
- 3. 1. 3. ΠΠ΅ΠΎΠ±Ρ ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ Π³Π»ΡΡΠ°ΠΌΠ°ΡΠ½ΠΎΠΉ ΡΠΈΠ½Π°ΠΏΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠ΅ΡΠ΅Π΄Π°ΡΠΈ
- 3. 1. 4. Π€Π»ΡΡΠ΅Π½Π°ΠΌΠΎΠ²Π°Ρ ΠΊΠΈΡΠ»ΠΎΡΠ° Π±Π»ΠΎΠΊΠΈΡΡΠ΅Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
- 3. 1. 5. Π ΠΈΠ»ΡΠ·ΠΎΠ» Π±Π»ΠΎΠΊΠΈΡΡΠ΅Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
- 3. 1. 6. Π£ΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΊΡΡΡΠ°ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΡ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΡΡΠΈΠ»Π΅Π½ΠΈΡ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅
- 3. 2. Π‘ΠΎΠ±ΡΡΠ²Π΅Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ
ΠΊΡΡΡ
- 3. 2. 1. Π’ΡΠΈ ΡΠΈΠΏΠ° ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ²
- 3. 2. 2. ΠΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° ΠΏΠ°ΡΠ΅ΡΠ½ΡΡ ΠΊΠ»Π΅ΡΠΎΠΊ Ρ ΠΏΡΡΠΎΠ³ΠΎ ΠΏΠΎ ΡΡΠΈΠ½Π°Π΄ΡΠ°ΡΡΠΉ Π΄Π΅Π½Ρ ΠΆΠΈΠ·Π½ΠΈ
- 3. 2. 3. Π Π΅Π³ΠΈΡΡΡΠ°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ΅ΠΆΠΈΠΌΠ΅ cell attached
- 3. 2. 4. ΠΠ»Π°ΡΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π° ΠΏΠ°ΡΠ΅ΡΠ½ΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ²
- 3. 2. 5. ΠΠ°ΡΠ΅ΡΠ½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π·Π°Π²ΠΈΡΠΈΡ ΠΎΡ Π²Π½ΡΡΡΠΈΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΡ
- 3. 2. 6. ΠΠ½ΠΈΡΠΈΠ°ΡΠΈΡ ΠΈ Π³Π΅Π½Π΅ΡΠ°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΠΈ ΠΏΠ»Π°ΡΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π°: ΠΈΠΎΠ½Π½ΡΠ΅ ΡΠΎΠΊΠΈ
- 3. 2. 7. Π’Π΅ΡΠΌΠΈΠ½Π°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΠΈ ΠΏΠ»Π°ΡΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π°: ΠΈΠΎΠ½Π½ΡΠ΅ ΡΠΎΠΊΠΈ
- 3. 2. 8. ΠΠ΅Π½Π΅ΡΠ°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π° ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠ΅ΠΉ ΠΈΠΎΠ½Π½ΡΡ ΡΠΎΠΊΠΎΠ²: ΡΡ Π΅ΠΌΠ°ΡΠΈΡΠ½ΠΎΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΠ΅
- 3. 2. 9. ΠΠ°ΡΠ΅ΡΠ½ΡΠ΅ ΠΏΠ΅ΠΉΡΠΌΠ΅ΠΊΠ΅ΡΠ½ΡΠ΅ Π½Π΅ΠΉΡΠΎΠ½Ρ ΠΌΠΎΠ³ΡΡ Π»Π΅ΠΆΠ°ΡΡ Π² ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ ΡΠ΅ΡΠ΅Π²ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ
- 3. 3. ΠΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ²
- 3. 3. 1. Π ΠΎΠ»ΠΈ ΠΈΠΎΠ½Π½ΡΡ ΡΠΎΠΊΠΎΠ²
- 3. 3. 2. ΠΠΎΠ΄Π΅Π»Ρ Π²ΠΎΡΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΡΠ΅Π°Π»ΡΠ½ΡΡ ΠΊΠ»Π΅ΡΠΎΠΊ
- 3. 3. 3. Π£ΡΠΈΠ»Π΅Π½ΠΈΠ΅ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΏΡΠΈ ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΡΠΊΡΡΡΠ°ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΡ ΠΎΠ±ΡΡΡΠ½ΡΠ΅ΡΡΡ ΡΠ²ΠΎΠΉΡΡΠ²Π°ΠΌΠΈ NaP ΡΠΎΠΊΠ°
- 3. 3. 4. ΠΠΏΠΈΡΠ°Π½ΠΈΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈ
Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π½Π΅ΠΉΡΠΎΠ½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΊΡΡΡ (ΡΠ΅ΡΠ΅ΡΠ°Ρ, ΠΊΡΡΡΠΎΠ²Π°Ρ, Π΄ΠΈΠΏΠ»ΠΎΠΌ, ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½Π°Ρ)
ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ.
Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΡΠ»ΠΈΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅ΡΡΠΎΠΉ ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅ΠΉΡΡ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ. Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π°Π±Π»ΡΠ΄Π°Π΅ΡΡΡ ΡΠΆΠ΅ Ρ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ ΠΏΡΠ΅Π΄ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΈΠΊΠΎΠ² (Spitzer, 2006). ΠΠ±ΡΡΠ½ΠΎ ΡΠ°ΠΊΠ°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ΅Π³ΠΈΡΡΡΠΈΡΡΠ΅ΡΡΡ ΠΊΠ°ΠΊ ΡΠ»ΡΠΊΡΡΠ°ΡΠΈΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ Π²Π½ΡΡΡΠΈΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΡ ΠΈΠ»ΠΈ ΠΊΠ°Π»ΡΡΠΈΠ΅Π²ΡΠ΅ ΡΠΏΠ°ΠΉΠΊΠΈ (Spitzer, 2006; Crepel et al., 2007). Π‘ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΏΠ΅ΡΠ²ΡΡ ΠΊΠΎΠ½ΡΠ°ΠΊΡΠΎΠ² ΠΌΠ΅ΠΆΠ΄Ρ Π½Π΅ΠΉΡΠΎΠ½Π°ΠΌΠΈ, ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΠ½Π°ΠΏΡΠΎΠ², ΠΏΠΎΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠΈΠ½Ρ ΡΠΎΠ½ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½Π°Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ. ΠΠ°Π»Π΅Π΅ Ρ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ Π² ΠΎΠ½ΡΠΎΠ³Π΅Π½Π΅Π·Π΅ Ρ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΠ½Π°ΠΏΡΠΎΠ² ΠΏΠΎΡΠ²Π»ΡΡΡΡΡ Π½ΠΎΠ²ΡΠ΅ Π²ΠΈΠ΄Ρ ΡΠΈΠ½Ρ ΡΠΎΠ½Π½ΠΎΠΉ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ (Crepel et al., 2007; Aliene et al., 2008). ΠΠ°ΡΠΈΠ½Π°Ρ Ρ ΠΌΠΎΠΌΠ΅Π½ΡΠ° ΠΏΠΎΡΠ²Π»Π΅Π½ΠΈΡ Ρ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΠ½Π°ΠΏΡΠΎΠ² ΡΠΈΠ½Ρ ΡΠΎΠ½Π½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΠΌΠΎΠΆΠ½ΠΎ ΡΡΠΈΡΠ°ΡΡ ΡΠ΅ΡΠ΅Π²ΠΎΠΉ Π² ΠΎΠ±ΡΡΠ½ΠΎΠΌ ΡΠΌΡΡΠ»Π΅ ΡΠ»ΠΎΠ²Π°. Π‘ΠΈΠ½Ρ ΡΠΎΠ½ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½Π°Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ ΡΠΌΠ±ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΏΠΎΡΡΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎ ΠΈΠ·ΡΡΠ°Π»Π°ΡΡ Π²ΠΎ ΠΌΠ½ΠΎΠ³ΠΈΡ ΡΡΡΡΠΊΡΡΡΠ°Ρ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΏΠΎΠ·Π²ΠΎΠ½ΠΎΡΠ½ΡΡ ΠΊΠ°ΠΊ in vitro, ΡΠ°ΠΊ ΠΈ in vivo, Π² ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ, Π½Π° Π³ΠΈΠΏΠΏΠΎΠΊΠ°ΠΌΠΏΠ΅, ΠΊΠΎΡΠ΅, ΡΠ΅ΡΡΠ°ΡΠΊΠ΅ ΠΈ ΡΠΏΠΈΠ½Π½ΠΎΠΌ ΠΌΠΎΠ·Π³Π΅. ΠΡΠ΅Π΄ΠΏΠΎΠ»Π°Π³Π°Π΅ΡΡΡ, ΡΡΠΎ ΡΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΈΠ³ΡΠ°Π΅Ρ ΠΊΠ»ΡΡΠ΅Π²ΡΡ ΡΠΎΠ»Ρ ΠΏΡΠΈ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Π½Π΅ΠΉΡΠΎΡΠ΅ΡΠΈ ΠΈ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² (Katz and Shatz, 1996). ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΡΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ΅ΡΡΠ°ΡΠΊΠΈ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ ΡΠΌΠ±ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π½Π΅ΠΎΠ±Ρ ΠΎΠ΄ΠΈΠΌΠ° Π΄Π»Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠΎΠΏΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΡΠ²ΡΠ·Π΅ΠΉ Π² ΡΠΎΡΠΌΠΈΡΡΡΡΠ΅ΠΉΡΡ Π·ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠ΅ (Sretavan et al., 1988; Grubb et al., 2003; McLaughlin et al., 2003; Chandrasekaran et al., 2005; Mrsic-Flogel et al., 2005; Torborg et al., 2005). Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΌΠΎΡΠΎΠ½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΡΠΏΠΈΠ½Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° Ρ ΡΠΌΠ±ΡΠΈΠΎΠ½ΠΎΠ² Π²Π»ΠΈΡΠ΅Ρ Π½Π° ΠΏΡΡΡ ΡΠΎΡΡΠ° Π°ΠΊΡΠΎΠ½ΠΎΠ² ΠΊ ΠΈΡ ΡΠ΅Π»ΡΠΌ (Hanson and Landmesser, 2004, 2006). Π Π³ΠΈΠΏΠΏΠΎΠΊΠ°ΠΌΠΏΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΡΠ°ΠΊ Π½Π°Π·ΡΠ²Π°Π΅ΠΌΡΠ΅ Π³ΠΈΠ³Π°Π½ΡΡΠΊΠΈΠ΅ Π΄Π΅ΠΏΠΎΠ»ΡΡΠΈΠ·Π°ΡΠΈΠΎΠ½Π½ΡΠ΅ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Ρ ΡΠΏΠΎΡΠΎΠ±Π½Ρ Π²ΡΠ·ΡΠ²Π°ΡΡ Π΄ΠΎΠ»Π³ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°ΡΠΈΡ ΡΠΎΡΠΌΠΈΡΡΡΡΠΈΡ ΡΡ «ΠΌΠΎΠ»ΡΠ°ΡΠΈΡ » ΡΠΈΠ½Π°ΠΏΡΠΎΠ² (Kasyanov et al., 2004; Mohajerani and Cherubini, 2006; Mohajerani et al., 2007). ΠΠΎΠ½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠ° Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠΈΡ ΡΡ ΠΈΠ΅ΠΉΡΠΎΡΠ΅ΡΡΡ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅ΡΡΡ ΡΡΠ½Π΄Π°ΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π°ΡΡΠ½ΠΎΠΉ Π·Π°Π΄Π°ΡΠ΅ΠΉ, ΠΏΠΎΡΠΊΠΎΠ»ΡΠΊΡ, ΠΊΠ°ΠΊ Π±ΡΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΠ²Π»Π΅Π½ΠΈΠ΅ Π½Π΅ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡΡ ΠΊΠ°ΠΊΠΎΠΉ-ΡΠΎ ΠΎΠ΄Π½ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ, Π° ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ ΠΎΠ±ΡΡΡ ΡΠ΅Π½Π΄Π΅Π½ΡΠΈΡ. Π Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²Π΅ ΡΠ°Π±ΠΎΡ Π½Π° ΡΡΠ΅Π·Π°Ρ ΠΊΠΎΡΡ ΠΈ Π³ΠΈΠΏΠΏΠΎΠΊΠ°ΠΌΠΏΠ° ΠΈΠ·ΡΡΠ°Π»ΠΈΡΡ, Π³Π»Π°Π²Π½ΡΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, ΡΠΈΠ½Π°ΠΏΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠΈΠ΅ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠΈΠ½Π°ΠΏΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠ΅ΡΠ΅Π΄Π°ΡΠΈ (Ben-Ari et al. 1989; Bolea et al. 1999; Gaiarsa et al. 1991; Hollrigel et al. 1998; Khazipov et al. 2001; Lamsa et al. 2000; Aliene et al., 2008). ΠΠ°ΠΏΡΠΈΠΌΠ΅Ρ, Π±ΡΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Ρ ΡΠΌΠ±ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΡ ΠΈ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ Π³Π»ΠΈΡΠΈΠ½ ΠΈ ΠΠΠΠ ΠΎΠ±Π»Π°Π΄Π°ΡΡ Π½Π΅ΠΎΠ±ΡΡΠ½ΡΠΌ Π΄Π΅ΠΏΠΎΠ»ΡΡΠΈΠ·ΡΡΡΠΈΠΌ Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ΠΌ (Ben-Ari et al. 1989; Ben-Ari, 2002; Ben-Ari et al., 2007). ΠΡΠΈ ΡΡΠΎΠΌ ΡΠ»Π΅ΠΊΡΡΠΎΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΡΠΎΠ·ΡΠ΅Π²Π°ΡΡΠΈΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΠΈ ΠΈΡ ΡΠΎΠ»Ρ Π² Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΎΡΡΠ°ΡΡΡΡ ΠΌΠ°Π»ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Π½ΡΠΌΠΈ.
Π¦Π΅Π»ΠΈ ΠΈ Π·Π°Π΄Π°ΡΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ.
ΠΡΠ½ΠΎΠ²Π½ΠΎΠΉ ΡΠ΅Π»ΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΡΠ²Π»ΡΠ»ΠΎΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈ ΡΠ²ΠΎΠΉΡΡΠ² ΡΠΎΠ·ΡΠ΅Π²Π°ΡΡΠΈΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠ»Π΅ΠΊΡΡΠΎΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΠΈ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ², Π° ΡΠ°ΠΊΠΆΠ΅ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ.
Π ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ ΠΏΠΎΡΡΠ°Π²Π»Π΅Π½Π½ΠΎΠΉ ΡΠ΅Π»ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΡΠ»Π΅Π΄ΡΡΡΠΈΠ΅ Π·Π°Π΄Π°ΡΠΈ:
1. Π‘ΡΠ°Π²Π½ΠΈΡΡ ΡΠ²ΠΎΠΉΡΡΠ²Π° Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΈ Π²Π·ΡΠΎΡΠ»ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ Π² ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Ρ Ρ ΡΠ΅Π³ΠΈΡΡΡΠ°ΡΠΈΠ΅ΠΉ Π²Π½ΡΡΡΠΈΠΊΠ»Π΅ΡΠΎΡΠ½ΡΡ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΠΎΠ².
2. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΡΡ ΡΠΎΠ»Ρ ΠΏΠ°ΡΠ΅ΡΠ½ΡΡ ΠΏΠ΅ΠΉΡΠΌΠ΅ΠΊΠ΅ΡΠ½ΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ .
3. ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ Π΄Π°Π½Π½ΡΡ ΠΏΠΎΡΡΡΠΎΠΈΡΡ ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΡΡ ΠΌΠΎΠ΄Π΅Π»Ρ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ .
ΠΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ, Π²ΡΠ½ΠΎΡΠΈΠΌΡΠ΅ Π½Π° Π·Π°ΡΠΈΡΡ.
1. ΠΠΈΡΠ°ΠΌΠΈΠ΄Π½ΡΠ΅ Π½Π΅ΠΉΡΠΎΠ½Ρ Π² ΡΡΠ΅ΡΡΠ΅ΠΌ ΡΠ»ΠΎΠ΅ ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Ρ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ. Π‘ΠΎΠ±ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΏΠ°ΡΠ΅ΡΠ½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΡΡΠ΅ΡΡΠ΅Π³ΠΎ ΡΠ»ΠΎΡ ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΊΡΡΡ (Π 5-Π 13) ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π° ΠΊΠΎΡΠΎΡΠΊΠΈΠΌΠΈ (Π΄ΠΎ 1 ΡΠ΅ΠΊ) ΠΈ Π΄Π»ΠΈΠ½Π½ΡΠΌΠΈ (Π΄ΠΎ 20 ΡΠ΅ΠΊ) ΠΏΠ°ΡΠΊΠ°ΠΌΠΈ ΡΠΏΠ°ΠΉΠΊΠΎΠ². ΠΠΎΡΠΎΡΠΊΠΈΠ΅ ΠΏΠ°ΡΠΊΠΈ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΏΠΎΠ»Π½ΠΎΡΡΡΡ ΠΏΡΠΎΠΏΠ°Π΄Π°ΡΡ ΠΊ Π΄Π΅ΡΡΡΠΎΠΌΡ Π΄Π½Ρ ΠΆΠΈΠ·Π½ΠΈ, Π° ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΊΠ»Π΅ΡΠΎΠΊ Π³Π΅Π½Π΅ΡΠΈΡΡΡΡΠΈΡ Π΄Π»ΠΈΠ½Π½ΡΠ΅ ΠΏΠ°ΡΠΊΠΈ Π΄ΠΎΡΡΠΈΠ³Π°Π΅Ρ ΠΌΠ°ΠΊΡΠΈΠΌΡΠΌΠ° Π½Π° Π 8-Π 10 ΠΈ Π·Π°ΡΠ΅ΠΌ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠΌΠ΅Π½ΡΡΠ°Π΅ΡΡΡ. ΠΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠ»Π΅ΠΊΡΡΠΎΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠ²ΠΎΠΉΡΡΠ² Ρ Π²ΠΎΠ·ΡΠ°ΡΡΠΎΠΌ ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΠ΅ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ².
2. ΠΠ΅Π½Π΅ΡΠ°ΡΠΈΡ Π΄Π»ΠΈΠ½Π½ΡΡ ΠΏΠ°ΡΠ΅ΠΊ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡ ΠΏΡΠΈ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ Π½Π΅ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΠΉ-Π·Π°Π²ΠΈΡΠΈΠΌΠΎΠ³ΠΎ CAN ΠΈ ΠΌΠ΅Π΄Π»Π΅Π½Π½ΠΎΠ³ΠΎ Π½Π°ΡΡΠΈΠ΅Π²ΠΎΠ³ΠΎ NaP ΡΠΎΠΊΠΎΠ². Π’Π΅ΡΠΌΠΈΠ½Π°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π° Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠ΅ΠΉ ΠΊΠ°Π»ΠΈΠ΅Π²ΡΡ ΡΠΎΠΊΠΎΠ².
ΠΠ°ΡΡΠ½Π°Ρ Π½ΠΎΠ²ΠΈΠ·Π½Π°.
Π ΡΠ°ΠΌΠΊΠ°Ρ Π½Π°ΡΡΠΎΡΡΠ΅ΠΉ ΡΠ°Π±ΠΎΡΡ Π²ΠΏΠ΅ΡΠ²ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Ρ ΡΠ²ΠΎΠΉΡΡΠ²Π° Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΡΠ΅ΡΡΠ΅ΠΌ ΡΠ»ΠΎΠ΅ ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Ρ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ . ΠΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΎ, ΡΡΠΎ Π±ΠΎΠ»ΡΡΠ°Ρ ΡΠ°ΡΡΡ ΠΏΠΈΡΠ°ΠΌΠΈΠ΄Π½ΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Ρ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΊΡΡΡ ΠΎΠ±Π»Π°Π΄Π°Π΅Ρ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ. ΠΡΡΠ΅Π·Π½ΠΎΠ²Π΅Π½ΠΈΠ΅ ΡΡΠΎΠ³ΠΎ ΡΠ²ΠΎΠΉΡΡΠ²Π° Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Ρ Π²ΠΎΠ·ΡΠ°ΡΡΠΎΠΌ ΠΆΠΈΠ²ΠΎΡΠ½ΠΎΠ³ΠΎ ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΠ΅ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ². ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΈΠΎΠ½Π½ΡΠ΅ ΡΠΎΠΊΠΈ, Π»Π΅ΠΆΠ°ΡΠΈΠ΅ Π² ΠΎΡΠ½ΠΎΠ²Π΅ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΠ»Π΅ΡΠΎΠΊ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ . ΠΠ΅Π½Π΅ΡΠ°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡ ΠΏΡΠΈ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ Π΄Π΅ΠΈ Π³ΠΈΠΏΠ΅ΡΠΏΠΎΠ»ΡΡΠΈΠ·ΡΡΡΠΈΡ ΠΈΠΎΠ½Π½ΡΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΡΡΠ΅ΠΉ. ΠΠΎΡΡΡΠΎΠ΅Π½Π° Π±ΠΈΠΎΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΌΠΎΠ΄Π΅Π»Ρ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ², Π²ΠΎΡΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ°Ρ Π²ΡΠ΅ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΡΠ΅Π°Π»ΡΠ½ΡΡ ΠΊΠ»Π΅ΡΠΎΠΊ. ΠΠΎΡΡΠ΅Π΄ΡΡΠ²ΠΎΠΌ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΡΡ Π΄Π°Π½Π½ΡΡ ΡΠ΄Π°Π»ΠΎΡΡ ΠΎΠ±ΡΡΡΠ½ΠΈΡΡ ΡΡΡΠ΅ΠΊΡ ΡΡΠΈΠ»Π΅Π½ΠΈΡ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΠΏΡΠΈ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΡΠΊΡΡΡΠ°ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΡ.
ΠΠ°ΡΡΠ½ΠΎ-ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠ΅Π½Π½ΠΎΡΡΡ ΡΠ°Π±ΠΎΡΡ.
ΠΠΎΠ»ΡΡΠ΅Π½Ρ Π½ΠΎΠ²ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΎ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΠΈ Π½Π΅ΠΉΡΠΎΡΠ΅ΡΠΈ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΏΠΎΡΡΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ, Π½Π΅ΠΎΠ±Ρ ΠΎΠ΄ΠΈΠΌΡΠ΅ Π΄Π»Ρ ΠΏΠΎΠ½ΠΈΠΌΠ°Π½ΠΈΡ Π½Π΅ΠΉΡΠΎΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΠΎΡΠ½ΠΎΠ² ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ. ΠΠ°ΡΠΈ Π΄Π°Π½Π½ΡΠ΅ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π°ΡΡ ΠΈΠ΄Π΅Ρ ΠΎ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΠΈ Π½Π΅ΠΉΡΠΎΡΠ΅ΡΠΈ ΠΎΡ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΠ»Π΅ΡΠΎΠΊ. ΠΠ½Π°Π»ΠΈΠ· ΡΠ²ΠΎΠΉΡΡΠ² Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Ρ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΡΠ°ΡΡΠΈΡΡΠ΅Ρ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΡ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΡΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠ°Ρ ΡΠ°ΠΌΠΎΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΡΡΡΠΊΡΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Π½Π΅ΠΉΡΠΎΡΠ΅ΡΠΈ. Π‘ΠΎΠ²ΠΎΠΊΡΠΏΠ½ΠΎΡΡΡ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΡ Π΄Π°Π½Π½ΡΡ ΠΌΠΎΠΆΠ΅Ρ Π½Π°ΠΉΡΠΈ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΏΡΠΈ ΠΊΠΎΠ½ΡΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΡΠΊΡΡΡΡΠ²Π΅Π½Π½ΡΡ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ ΡΠ΅ΡΠ΅ΠΉ.
ΠΠΏΡΠΎΠ±Π°ΡΠΈΡ ΡΠ°Π±ΠΎΡΡ.
ΠΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ°Π±ΠΎΡΡ Π±ΡΠ»ΠΈ Π΄ΠΎΠ»ΠΎΠΆΠ΅Π½Ρ Π½Π° ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ ΡΠΎΡΡΠΌΠ°Ρ ΠΠ Π (ΠΡΠ»Π°Π½ΡΠ° 2006, Π‘Π°Π½ ΠΠΈΠ΅Π³ΠΎ 2007, Π§ΠΈΠΊΠ°Π³ΠΎ 2009) — XX Π‘ΡΠ΅Π·Π΄Π΅ ΡΠΎΡΡΠΈΠΉΡΠΊΠΈΡ ΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΎΠ² (ΠΠΎΡΠΊΠ²Π°, 2007) — Π½Π° ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΡΡ ΠΌΠΎΠ»ΠΎΠ΄ΡΡ ΡΡΠ΅Π½ΡΡ ΠΠΠΠ ΠΈ ΠΠ€ Π ΠΠ (ΠΠΎΡΠΊΠ²Π°, 2006, 2008). ΠΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΡ Π°ΠΏΡΠΎΠ±ΠΈΡΠΎΠ²Π°Π½Π° 13 ΠΎΠΊΡΡΠ±ΡΡ 2009 Π³ΠΎΠ΄Π° Π½Π° ΡΠΎΠ²ΠΌΠ΅ΡΡΠ½ΠΎΠΌ Π·Π°ΡΠ΅Π΄Π°Π½ΠΈΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠΈΠΈ ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠΉ Π½Π΅ΠΉΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ ΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠΈΠΈ Π½Π΅ΠΉΡΠΎΠΎΠ½ΡΠΎΠ³Π΅Π½Π΅Π·Π° ΠΠ½ΡΡΠΈΡΡΡΠ° Π²ΡΡΡΠ΅ΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΈ Π½Π΅ΠΉΡΠΎΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ Π ΠΠ.
ΠΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΈ.
ΠΠΎ ΡΠ΅ΠΌΠ΅ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΈ ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½ΠΎ 2 ΡΡΠ°ΡΡΠΈ ΠΈ ΡΠ΅Π·ΠΈΡΡ 6 Π΄ΠΎΠΊΠ»Π°Π΄ΠΎΠ².
Π‘ΡΡΡΠΊΡΡΡΠ° ΠΈ ΠΎΠ±ΡΠ΅ΠΌ ΡΠ°Π±ΠΎΡΡ.
ΠΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΡ ΡΠΎΡΡΠΎΠΈΡ ΠΈΠ· Π²Π²Π΅Π΄Π΅Π½ΠΈΡ, ΠΎΠ±Π·ΠΎΡΠ° Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ, ΠΎΠΏΠΈΡΠ°Π½ΠΈΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ, ΠΈΠ·Π»ΠΎΠΆΠ΅Π½ΠΈΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ², ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΡ, Π²ΡΠ²ΠΎΠ΄ΠΎΠ² ΠΈ ΡΠΏΠΈΡΠΊΠ° Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ (204 ΡΡΡΠ»ΠΊΠΈ). Π Π°Π±ΠΎΡΠ° ΠΈΠ·Π»ΠΎΠΆΠ΅Π½Π° Π½Π° 131 ΡΡΡΠ°Π½ΠΈΡΠ΅, Π²ΠΊΠ»ΡΡΠ°Π΅Ρ 27 ΡΠΈΡΡΠ½ΠΊΠΎΠ² ΠΈ 8 ΡΠ°Π±Π»ΠΈΡ.
Π²ΡΠ²ΠΎΠ΄Ρ.
1. ΠΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½Π°Ρ ΠΊΠΎΡΠ° Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΡΠΏΠΎΡΠΎΠ±Π½Π° Π³Π΅Π½Π΅ΡΠΈΡΠΎΠ²Π°ΡΡ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΠΎ ΠΎΡ Π³ΠΈΠΏΠΏΠΎΠΊΠ°ΠΌΠΏΠ° ΠΈ Π΄ΡΡΠ³ΠΈΡ ΡΡΡΡΠΊΡΡΡ ΠΌΠΎΠ·Π³Π°.
2. Π‘ΠΏΠΎΠ½ΡΠ°Π½Π½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π° ΠΊΠΎΡΠΎΡΠΊΠΈΠΌΠΈ ΠΈ Π΄Π»ΠΈΠ½Π½ΡΠΌΠΈ ΡΠ΅ΡΠ΅Π²ΡΠΌΠΈ ΡΠ°Π·ΡΡΠ΄Π°ΠΌΠΈ, Π³Π΅Π½Π΅ΡΠ°ΡΠΈΡ ΠΊΠΎΡΠΎΡΡΡ ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡ Π·Π° ΡΡΠ΅Ρ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ ΠΊΠ°ΠΊ ΠΠΠΠ-, ΡΠ°ΠΊ ΠΈ Π³Π»ΡΡΠ°ΠΌΠ°ΡΠ΅ΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΠ½Π°ΠΏΡΠΎΠ².
3. Π£ΠΆΠ΅ Π½Π° ΠΏΡΡΡΠΉ Π΄Π΅Π½Ρ ΠΆΠΈΠ·Π½ΠΈ ΠΠΠΠ ΡΠ°ΡΡΠΈΡΠ½ΠΎ Π²ΡΠΏΠΎΠ»Π½ΡΠ΅Ρ ΡΠΎΡΠΌΠΎΠ·Π½ΡΡ ΡΡΠ½ΠΊΡΠΈΡ, ΠΏΠΎΡΠΊΠΎΠ»ΡΠΊΡ Π±Π»ΠΎΠΊΠΈΡΠΎΠ²ΠΊΠ° ΠΠΠΠ, Π ΡΠ΅ΡΠ΅ΠΏΡΠΎΡΠΎΠ² ΡΡΠ°Π½ΡΡΠΎΡΠΌΠΈΡΡΠ΅Ρ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Π² ΡΡΠ΄ΠΎΡΠΎΠΆΠ½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ.
4. ΠΠ»Ρ Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ Π½Π΅ΠΎΠ±Ρ ΠΎΠ΄ΠΈΠΌΠ° Π³Π»ΡΡΠ°ΠΌΠ°ΡΠ΅ΡΠ³ΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠΈΡΡΠ΅ΠΌΠ°, ΠΏΠΎΡΠΊΠΎΠ»ΡΠΊΡ Π±Π»ΠΎΠΊΠΈΡΠΎΠ²ΠΊΠ° ΠΠΠΠ/ΠΊΠ°ΠΈΠ½Π°ΡΠ½ΡΡ ΠΈ ΠΠΠΠ ΡΠ΅ΡΠ΅ΠΏΡΠΎΡΠΎΠ² ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΠΈΡΡΠ΅Π·Π½ΠΎΠ²Π΅Π½ΠΈΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΏΡΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΠΎΠΉ Π²ΠΎΠ·Π±ΡΠ΄ΠΈΠΌΠΎΡΡΠΈ ΡΡΠ΅Π·Π°.
5. ΠΠΈΡΠ°ΠΌΠΈΠ΄Π½ΡΠ΅ Π½Π΅ΠΉΡΠΎΠ½Ρ Π² ΡΡΠ΅ΡΡΠ΅ΠΌ ΡΠ»ΠΎΠ΅ ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Ρ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠ΅ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ. Π£ Π²Π·ΡΠΎΡΠ»ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ Π½ΠΈ ΠΎΠ΄ΠΈΠ½ ΡΠΈΠΏ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅ ΡΠ°ΠΊΠΈΠΌ ΡΠ²ΠΎΠΉΡΡΠ²ΠΎΠΌ Π½Π΅ ΠΎΠ±Π»Π°Π΄Π°Π΅Ρ.
6. Π‘ΠΎΠ±ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΏΠ°ΡΠ΅ΡΠ½Π°Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² ΡΡΠ΅ΡΡΠ΅Π³ΠΎ ΡΠ»ΠΎΡ ΡΠ½ΡΠΎΡΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΡ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ ΠΊΡΡΡ (Π 5-Π 13) ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π° ΠΊΠΎΡΠΎΡΠΊΠΈΠΌΠΈ (Π΄ΠΎ 1 ΡΠ΅ΠΊ) ΠΈ Π΄Π»ΠΈΠ½Π½ΡΠΌΠΈ (Π΄ΠΎ 20 ΡΠ΅ΠΊ) ΠΏΠ°ΡΠΊΠ°ΠΌΠΈ ΡΠΏΠ°ΠΉΠΊΠΎΠ². ΠΠ°ΡΠ΅ΡΠ½ΡΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΠΊΠ»Π΅ΡΠΎΠΊ Π±ΡΡΡΡΠΎ ΠΌΠ΅Π½ΡΡΡΡΡ Ρ Π²ΠΎΠ·ΡΠ°ΡΡΠΎΠΌ, ΡΡΠΎ ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΠ΅ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ². ΠΠΎΡΠΎΡΠΊΠΈΠ΅ ΠΏΠ°ΡΠΊΠΈ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΏΠΎΠ»Π½ΠΎΡΡΡΡ ΠΏΡΠΎΠΏΠ°Π΄Π°ΡΡ ΠΊ Π΄Π΅ΡΡΡΠΎΠΌΡ Π΄Π½Ρ ΠΆΠΈΠ·Π½ΠΈ, Π° ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΊΠ»Π΅ΡΠΎΠΊ Π³Π΅Π½Π΅ΡΠΈΡΡΡΡΠΈΡ Π΄Π»ΠΈΠ½Π½ΡΠ΅ ΠΏΠ°ΡΠΊΠΈ Π΄ΠΎΡΡΠΈΠ³Π°Π΅Ρ ΠΌΠ°ΠΊΡΠΈΠΌΡΠΌΠ° Π½Π° Π 8-Π 10 ΠΈ Π·Π°ΡΠ΅ΠΌ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠΌΠ΅Π½ΡΡΠ°Π΅ΡΡΡ.
7. Π ΠΎΡΠ²Π΅Ρ Π½Π° ΠΊΠΎΡΠΎΡΠΊΠΈΠΉ Π΄Π΅ΠΏΠΎΠ»ΡΡΠΈΠ·ΡΡΡΠΈΠΉ ΠΈΠΌΠΏΡΠ»ΡΡ ΡΠΎΠΊΠ° Π΄Π»ΠΈΠ½Π½ΠΎΠΏΠ°ΡΠ΅ΡΠ½ΡΠ΅ Π½Π΅ΠΉΡΠΎΠ½Ρ Π³Π΅Π½Π΅ΡΠΈΡΡΡΡ ΠΏΠ»Π°ΡΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π°, Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡΡ Π΄ΠΎ 10 ΡΠ΅ΠΊ, Ρ. Π΅. ΠΏΠ°ΡΠΊΡ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΌΠΎΠΆΠ½ΠΎ «Π²ΠΊΠ»ΡΡΠΈΡΡ» ΠΈΡΠΊΡΡΡΡΠ²Π΅Π½Π½ΠΎΠΉ Π²Π½ΡΡΡΠΈΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠΉ Π΄Π΅ΠΏΠΎΠ»ΡΡΠΈΠ·Π°ΡΠΈΠ΅ΠΉ.
8. ΠΠ΅Π½Π΅ΡΠ°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΈ ΠΏΠ»Π°ΡΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π° ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡ ΠΏΡΠΈ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ Π½Π΅ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΠΉ-Π·Π°Π²ΠΈΡΠΈΠΌΠΎΠ³ΠΎ CAN ΠΈ ΠΌΠ΅Π΄Π»Π΅Π½Π½ΠΎΠ³ΠΎ Π½Π°ΡΡΠΈΠ΅Π²ΠΎΠ³ΠΎ NaP ΡΠΎΠΊΠΎΠ². Π’Π΅ΡΠΌΠΈΠ½Π°ΡΠΈΡ ΠΏΠ°ΡΠ΅ΠΊ ΡΠΏΠ°ΠΉΠΊΠΎΠ² ΠΈ ΠΏΠ»Π°ΡΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π° ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π° Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠ΅ΠΉ ΠΊΠ°Π»ΠΈΠ΅Π²ΡΡ ΡΠΎΠΊΠΎΠ².
9. ΠΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΏΠ°ΡΠ΅ΡΠ½ΡΡ ΠΊΠ»Π΅ΡΠΎΠΊ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠ²Π΅Π»ΠΈΡΠΈΠ²Π°Π΅ΡΡΡ ΠΏΡΠΈ ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΡΠΊΡΡΡΠ°ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»ΡΡΠΈΡ. ΠΠΎΠ΄Π΅Π»ΡΠ½ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ, ΡΡΠΎ ΡΡΠΎ ΠΌΠΎΠΆΠ½ΠΎ ΠΎΠ±ΡΡΡΠ½ΠΈΡΡ ΡΠ²ΠΎΠΉΡΡΠ²Π°ΠΌΠΈ ΠΌΠ΅Π΄Π»Π΅Π½Π½ΠΎΠ³ΠΎ Π½Π°ΡΡΠΈΠ΅Π²ΠΎΠ³ΠΎ ΡΠΎΠΊΠ°.
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